In this issue of \u003ci\u003eClinics in Chest Medicine\u003c/i\u003e, guest editors Drs. Scott Evans, Guang-Shing Cheng, Julio Ramirez, and Bashar Staitieh bring their considerable expertise to the topic of \u003cb\u003ePulmonary Disease in the Immunocompromised Host\u003c/b\u003e. Top experts discuss imaging the immunocompromised lung; laboratory molecular testing in immunocompromised host pneumonia; vaccines and other preventative strategies for immunocompromised pneumonia; adjunctive/host-directed therapies in immunocompromised host pneumonia; sequelae of immunocompromised host pneumonia; and more.\u003cul\u003e\u003cli\u003eContains \u003cb\u003e16 relevant, practice-oriented topics\u003c/b\u003e including COVID-19 and emerging lung infections in the immunocompromised patient; pulmonary immunocompromise in stem cell transplantation and cellular therapy; pulmonary immunocompromise in solid organ transplantation; pulmonary immunocompromise in chronic and high dose steroid therapy; and more.\u003c/li\u003e\u003cli\u003eProvides in-depth \u003cb\u003eclinical reviews on pulmonary disease in the immunocompromised host\u003c/b\u003e, offering actionable insights for clinical practice.\u003c/li\u003e\u003cli\u003ePresents the \u003cb\u003elatest information on this timely, focused topic\u003c/b\u003e under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.\u003c/li\u003e\u003c/ul\u003e