\u003cp\u003eOffering \u003cb\u003eunique, comprehensive coverage of both basic science and clinical scenarios\u003c/b\u003e, \u003ci\u003eClinical Immunology: Principles and Practice, 6th Edition\u003c/i\u003e, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes \u003cb\u003ecomplete coverage of common and uncommon immunologic disorders\u003c/b\u003e. Updated with all the latest immunologic research and clinical implications, including \u003cb\u003ebreakthrough immunotherapies and molecular-based treatment protocols\u003c/b\u003e, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume.\u003c/p\u003e\u003cul\u003e \u003cli\u003eIncludes \u003cb\u003eextensive revisions that reflect rapidly expanding research and clinical advances\u003c/b\u003e, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine. \u003c/li\u003e \u003cp\u003e \u003cli\u003eContains \u003cb\u003enew chapters\u003c/b\u003e on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma.\u003c/li\u003e \u003cp\u003e \u003cli\u003eProvides \u003cb\u003enew genetics content\u003c/b\u003e focused on data applications.\u003c/li\u003e \u003cp\u003e \u003cli\u003eAddresses \u003cb\u003enotable advances in key areas\u003c/b\u003e such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. \u003c/li\u003e \u003cp\u003e \u003cli\u003eCovers \u003cb\u003ehot topics\u003c/b\u003e such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics.\u003c/li\u003e \u003cp\u003e \u003cli\u003eFeatures a \u003cb\u003euser-friendly format\u003c/b\u003e with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles.\u003c/li\u003e \u003cp\u003e \u003cli\u003eSummarizes \u003cb\u003epromising research and development\u003c/b\u003e anticipated over the next 5â10 years with \"On the Horizon\" boxes and discussions of translational research.\u003c/li\u003e \u003c/ul\u003e
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