Inhoudsopgave:
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\u003cp\u003e\u003ci\u003eEpigenetics and Reproductive Health,\u003c/i\u003e a new volume in the \u003ci\u003eTranslational Epigenetics\u003c/i\u003e series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. \u003c/p\u003e \u003cp\u003eLater chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics.\u003c/p\u003e\u003cul\u003e\u003cli\u003eThoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations\u003c/li\u003e\u003cli\u003eExplores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers\u003c/li\u003e\u003cli\u003eFeatures chapter contributions from international researchers in the field\u003c/li\u003e\u003c/ul\u003e |
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