\u003cp\u003e\u003ci\u003eAntimalarial Agents: Design and Mechanism of Action\u003c/i\u003e seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future.\u003c/p\u003e \u003cp\u003eMalaria is a deadly disease which threatens half of the worldâs population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential.\u003c/p\u003e \u003cp\u003eBeginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasiteâs genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs.\u003c/p\u003e \u003cp\u003eDrawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, \u003ci\u003eAntimalarial Agents: Design and Mechanism of Action\u003c/i\u003e is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists.\u003c/p\u003e\u003cul\u003e\u003cli\u003eConsolidates both past and current developments in the discovery and design of antimalarial drugs\u003c/li\u003e\u003cli\u003ePresents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds\u003c/li\u003e\u003cli\u003eHighlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected\u003c/li\u003e\u003c/ul\u003e
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